A set-it-and-forget-it slow cooker recipe featuring tender chuck roast cooked in a tangy, buttery sauce with ranch seasoning and pepperoncini peppers. Perfect for busy weeknights and comforting family meals.
Do not open the slow cooker lid during cooking to maintain heat and moisture. Butter is essential for the creamy, rich sauce. Use fresh pepperoncini peppers and their juice for best flavor. For a dairy-free version, substitute butter with vegan butter or olive oil. Leftovers store well in the fridge for up to 4 days or freeze for up to 3 months. To thicken sauce, use cornstarch slurry as described.
Keywords: Mississippi pot roast, slow cooker pot roast, easy pot roast, ranch seasoning, pepperoncini, comfort food, set and forget, weeknight dinner